ZO608 : Epigenetics

Department

Department of Zoology

Academic Program

Master in Evolutionary Biology

Type

Compulsory

Credits

03

Prerequisite

Overview

The student acquires new skills and techniques specific to synthesis scienc

· Understanding the mechanisms involved in genetic control

· Understand the importance of epigenetics in the process of gene expression, development and genome organization and stability.

Intended learning outcomes

أ.1

The student acquires the skill of laboratory techniques and methods of scientific research.

أ.2

Understanding genetic impact contributions to physical cloning, cancer and ageing

أ.3

Interpretation and design of experiments examining genetic inheritance cases that identify genetic pathways

Teaching and learning methods

Lectures

· Laboratory activities

· • Data collection

Methods of assessments

evaluation number

Evaluation methods

Evaluation period

assessing weight.

percentage

evaluation date(the week)

comments

First evaluation

midterm exam

2 hours

20

20%

seventh

Second evaluation

Scientific reports and presentations

40

40%

Semester length

Final evaluation

final exam

3hours

40

40%

Following the fourteenth week

the total

100 degree

100%

1. المراجع(References)

References address

publisher

Release

Author

located

Course notes

Springer Publishers

2 th edition

Jeanteur et al. (2008)

Prescribed textbooks

John Wiley & Sons, Inc

2th edition

Lizabeth A. Alison. (2012)

Help books

. Garland Science

3th edition

Bruce Alberts et al. (2010)

1. محتوى المقرر (Course contents)

اweek

1

scientific topic

number of hours

lecture

Lab

1-2

14

Intro to histones, chromatin packing, transcription factors and gene expression.

24

4

6

3

7

DNA methylation, histone modifications, and epigenetic regulators.

5

2

3

4

7

The epigenetic code for gene silencing.

5

2

3

5

7

The epigenetic code for gene activation and long-distance regulation

5

2

3

6

7

Imprinting & X-inactivation.

5

2

3

الامتحان النصفي

8

7

Transgenerational effects, twins, and development as epigenetic processes.

5

3

2

9

7

Polycomb Group (PcG) proteins and RNA-mediated heterochromatin formation

5

3

2

10

7

Development revisited: reprogramming in primordial germ cells (PGCs)

5

3

2

11

7

Induced pluripotent stem cells (iPSCs) and Ageing

5

3

2

12

7

Cancer epigenetics

5

3

2

13

7

Oral presentations and paper discussion

5

3

2

14

7

Neuroepigenetics

5

3

2

الامتحان النهائي