Central Axonal Response to Stretch Injury: An Immunohistochemical Study

الملخص

Diabetes mellitus is a chronic disorder characterized by impaired metabolism of glucose and it has many complications
affecting the micro vascular level of the eye and kidneys and a variety of clinical neuropathy. It is associated with
premature macro vascular diseases such as myocardial infarction and stroke, and peripheral vascular complications
leading to ischemia and necrosis with putrefaction of the lower limbs.
The objective of this study is to describe the clinical, pathophysiological findings and surgical management of diabetic
foot and how we can improve our outcomes and develop a guideline for the management of diabetic foot. It is a
retrospective study of data on a total number of 33 patients admitted to Breast and Endocrine Department at Tripoli
Medical Center over a one year period (from first of January 2014 to thirty one of December 2014).
We conclude that diabetic foot syndrome is a major complication of non-controlled diabetes mellitus which can
be prevented by education and proper management of diabetes mellitus. Amputation can be minimized in diabetic
patients by controlling blood sugar level, along with the administration of antibiotic and Debridement. Meropenem
(Meronem) was found to be more effective than any other antibiotics used in our study in treating diabetic foot
syndrome