Effect of Vitamin D Level on Glycemic Control in Diabetic Pregnant Women at Endocrine Clinic, Department of Gynecology and Obstetrics/ Tripoli Medical Center, Libya, 2016

Abstract

Vitamin D deficiency in pregnancy was related to the incidence of gestational diabetes (GDM) and serum 25(OH)
D was significantly lower in women with GDM than in those with normal glucose tolerance.
The study aimed to study the effect of vitamin D level on glycemic control in diabetic pregnant women.
This study was a longitudinal study. It was conducted at Obstetrics and Gynecology Department at Tripoli Medical
Center (TMC) during the year 2016 from March to August. Sixty diabetic pregnant women were included. Blood
level for vitamin D and HbA1c were measured before and after vitamin D supplementation. SPSS software version
16, used to analyze the data; mean, standard deviation, percentages and paired T test were used. P value < 0.05
considered significant. The mean age of the cases was 33.7 ± 6.3 years. Most of the patients 57 (95%) suffered
from Vitamin D deficiency and 3 (5%) patients have insufficient level. HbA1c level among 96.6% of patients was
> 7%. Mean of vitamin D prior supplementation was 9.3±6.45 ng/ml, increasing to 27.7±9.12 post treatment and
the mean of Hb A1C pre supplementation was 7.8±1.27 decreasing after treatment to 5.8±0.68.
There was a significant increase in vitamin D level after treatment (27.7±9.2) and significant decrease in HbA1c
after supplementation (5.83±0.68).
Identification of CAN is crucial because it can lead to severe morbidity and mortality and increase risk of sudden
cardiac death