Hemoglobin A1 Concentration of Diabetic Mother as a Predictor of Perinatal Morbidity and Mortality

Abstract

Prospective study of diabetic mothers delivered in obstetric department Alkhadra Hospital, Tripoli Libya during the period
from Jan 1st to Dec 31st 2005. 66 diabetic mothers were included in this study, 27 of them with gestational diabetes, 30
with insulin dependent diabetes (IDDM), and 9 with noninsulin dependent (NIDDM), mean age 31.6 years. They have
glycosylated hemoglobin (HbA1C) values > 8.5%. The study showed high values in early pregnancy were associated with
major neonatal congenital anomalies (2 cases), and in second and third trimesters were associated mainly with infants large
for gestational age (7 infants), and neonatal hypoglycemia (14 infants).