Molecular genetics of β-talassemia in Tripoli-Libya

المؤلفون

  • Marwan, M. M
  • Tabagh, R. M

الكلمات المفتاحية:

β-talassemia, DNA Sequencing, Libyan Adults, Tripoli

الملخص

β-talassemia is an inherted blood disorder, in which the body does not make as much as β-globin as it should be.  Hemoglobin is the part of a red blood cells (RBCs) that carries oxygen throughout the body.  β-talassemia includes three main forms, major, intermadia, and minor.  β-globin DNA mutations present in 14 subjects from 866 adult samples.  β-talassemia, major and minor were analyzed by DNA sequencing of amplified DNA.  Different β-talassemia mutations were identified.  The three common three β-talassemia found in Libya were B°CD39 (C→T) N=6, B+IVS-I,6 (C→T) N=5, and B+IVS-1,110 (G→A) N=3.

التنزيلات

منشور

2025-06-14

كيفية الاقتباس

Marwan, M. M و Tabagh, R. M (2025) "Molecular genetics of β-talassemia in Tripoli-Libya", المجلة الليبية للعلوم, 28(1). موجود في: https://uot.edu.ly/journals/index.php/ljs/article/view/1913 (تاريخ الوصول: 11 يوليو 2025).

إصدار

القسم

Zoology
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