Roles

More than 16 years at UOT and  I am one of the staff members at the department of the faculty of pharmacy  (my job is teaching and Research) in the Department of medicinal and pharmaceutical chemistry.

I have been participated in teaching several subjects in both undergraduate and postgraduate level in this field. and also  have several publications in the field of my interest.  

Careers

· 2021/2022  Voice dean for  scientific affairs.

2021/2022:

 Head of postgraduate office in Faculty of pharmacy, University of Tripoli, Tripoli, Libya.

2017-until Now:

Professor of  Medicinal Chemistry, Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

2013 – 2017:

Associate Professor of  Medicinal Chemistry, Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

2009 – 2013:

Assistant Professor of Medicinal Chemistry, Dept. of Medicinal & Pharmaceutical Chemistry,  Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

2006 – 2009:

Lecture of Medicinal Chemistry, Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

2003 – 2006:

Assistant Lecturer. of Medicinal Chemistry, Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

2017: Member of the scientific committee of Faculty of Pharmacy, University of  Tripoli, Tripoli, Libya.

Spring 2017: Head of the committee of the final examination of the faculty.

2014/2015

Chairman , Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, University of  Tripoli, Tripoli, Libya.

10/2013-2/2014:

Dean of Faculty,  University of Tripoli, Tripoli , Libya.

2012-2013:

Vice Dean for scientific Affair of Faculty of pharmacy, University of Tripoli, Tripoli, Libya.

2011-2012:

Chairman,  Dept. of Medicinal & Pharmaceutical Chemistry, Faculty of Pharmacy, Univ.of  Tripoli, Tripoli, Libya.

2009-2011:

Head of the quality control Lab,  University of Tripoli, Faculty of pharmacy Tripoli, Libya.

Research Interests

Medicinal & Pharmaceutical Chemistry courses for undergraduate students.

                                                                         Undergraduate:

*   Pharmaceutical Medicinal Chemistry: A standard course offered to the third and fourth year     class, Faculty of Pharmacy. Emphasis is on uses, syntheses, correlation of properties, structure and  

    biological activity for compounds of medicinal and pharmaceutical importance.

                                                                                                                                                                                  *

Spectrophotometric Identification of Pharmaceutical Compounds: The course deals with the

    principles and application of mass (MS) and infra-red (IR) spectrometry in the structural elucidation    

    of organic compounds.

* .   Advanced Medicinal Chemistry: A standard course offered to post graduate student, faculty of pharmacy, Correlation of properties, structure and biological activity for recent compounds of medicinal and pharmaceutical importance.

1.      Interested in the fields of Methylxanthine as adenosine receptor subtypes agonist and   antagonist .

2.  Interested in the fields of tricyclic theophylline derivatives as a potential agent acting on CNS and CVS.   

3.      Interested in the fields alkyl amide derivatives of tricyclic theophylline  as 5-HT1 and 5-HT2  agonist or antagonist.

4.     Synthesis and Biological Activity of Some New benzimdazole derivatives.

5.       Synthesis and Pharmacological properties of  Some New Phthalimide Derivatives as  potential agent acting on CNS and CVS.

6.      Synthesis and Pharmacological prosperities of Some New indole derivatives

7.      Synthesis and Biological activity of some new amide derivatives

8.      Synthesis and Biological Activity of some New indole & benzimdazole  Schiff's base 

9.      Synthesis and pharmacological activity of new succinimide derivatives.

10. I shred  on the activity performed abroad tempus Joint European Project; it was take place in Bonn, 11/1999.

11.  In Sep/ 2010  I participated in the  Drug design & computer modelling Workshop organized by National Medical centre at Alzawia.

External Activities

2004-2008:

Visiting Lecturer, Alzawia University, Faculty of pharmacy, Alzawia, Libya.

                                                                                                                                                                       2006-2009:

Visiting Lecturer, Almergab University, Faculty of pharmacy, Almergab, Libya.

                                                                                                                                                                        2005-2015

Supervising graduate research and teaching associate, Dept. of Medicinal Chemistry, Faculty of Pharmacy, University of Tripoli, Tripoli, Libya.

·    I Participated in teaching training courses good manufacturing practices (GMP) , which was held in  January 2018, organized by national institution for medical staff development

1.    Central nervous system activity of new pyrimidine-8-on[2,1-f] theophylline-9-alkylcarboxylic  

   acids derivatives

     Author(s) FHID ; PAWLOWSKI ; FILIPEK ; ...

     Polish journal of pharmacology 2002, 54, 245 – 254

2.      Pyrimidin-8-on[2,1-fltheophylline-9-alkylcarboxylic acids amides  as A1 and A2A adenosine

receptor ligands

                Author(s) FHID ; PAWLOWSKI; JURCZYK ; ...

     Il Farmaco (Pavia) 2003, 58, 439 – 444.

3.   Synthesis and 5-HT1A/5-HT2A activity of some butyl analogs in the group of  phenylpiperazine alkyl pyrimido [2,1-f]theophyllines

     Author(s) FHID O; ...KOLACZKOWSKI ; ZAJDEL ;

     Pharmacological reports 2005, 57, 229 – 235.

4. The cardiovascular properties of some amide derivatives of pyrimidin-8- on[2,1-

     f]theophylline-9-alkylcarboxylic acids

    Author(s) Zagórska ; Fhid ; Pawłowski ; ...

    Letters in drug design and discovery 2006, 3, 346 – 350

5.Synthesis and anticonvulsant properties of new amide derivatives  of pyrimidin-8-on [2,1-f]

theophylline  -9-alkylcarboxylic acids

     Author(s) O FHID ; Pawlowski P., K. Aroud…..

     Journal of basic  and applied science, 2005, 2, 15.

6. Methylxanthine as Adenosine Receptor Antagonists, An Overview.

     Author(s)  OMRAN FHID .

     Journal of basic and applied science-Libya:  2006

7.  Review article: Structure and function of A1 adenosine receptor

      Author(s)  Omran N. Fhid*, Talal H. Zeglam and Masoud A. Alag, Lib. J. Med. Res. 7,    

      2: 2010.

8.  Synthesis and antimicrobial activity of some novel amide derivatives

       Author(s)  T. H.  Zeglam1*, O. N.  Fhid1,  A. O . Jebril2 and  M. A. Anweir1 : 

       Tripolitania Medical Journal (2012); 1(1): 70-77.

9.  Synthesis and anticoagulant properties of new amide derivatives of  of pyrimido -8-  on [2,1-

     f]theophylline-9-alkylcarboxylic acids

  Author(s)  OMRAN FHID, Tarq Almog, PAWLOWSKI. Maceuj…

  International Journal of Pharmaceutical & Biological Archives,  2012: 3(3):

10  Synthesis, characterization and pharmacological evaluation of some  tricyclic-theophylline 

   derivatives

      Author(s) Omran. Fhid*, Muacij. Pawłowski, Beata Duszynska

      Journal  of Chemical and Pharmaceutical Research, 2012,4(5):2367-2372.

11.    Tri- and tetra- cyclic theophylline derivatives as a potential agent acting on CNS and   

   CVS: an   Overview.

   Author(s)  Omran N. Fhid*, Talal H. Zeglam and Masoud A. Alag……….,

       Journal of  International Journal of Pharmaceutical & Biological Archives,

       2012;3(3):507-512.

10.  Synthesis, characterization and biological evaluation of shciff,s bases

  Author(s) Omran Fhid, Talal Zeglam and Asma Jebril.

  Journal of pharmaceutical & scientific Innovation, 2014, 3, 10-13.

11.    Synthesis and pharmacological activity of some new α N-Phthalimido amino acids   

   analogues.

 Author(s) Omran. Fhid1*, Talal. H. Zeglam, Shapan. E. A. Saad, Asma. Eswayah, Tarek.   Elmug1, Hamza. S. Atia, Hamz. M. Ashur, Abdusalam. H. Alnaghnogy.

American Journal of Pharmacy and Pharmacology, 2014; 1(1): 1-5

12.    Synthesis, Characterization and Antiepileptic Activity of Some New N-Substituted   Phthalimide Analogs

 Author(s) Omran N. R. Fhid, Shaban E. A. Saad, Talal H. Zeglam, Asma Eswayah, Tariq Elmoug,  

 Esra Alnnas1, Yousra Haroon, Ahmed A. Eldep and Abdelhamed Ebzabez

 Journal of Life Sciences, April 2014, Vol. 8, No. 4, pp. 373-377

13.    Synthesis, characterization and pharmacological activity of some new phthalimide derivatives

      Author(s) Omran Fhid , Talal H. Zeglam , Shaban E. A. Saad, Tariq Elmoug , Asma Eswayah ,   

      Majda Zitouni, Wafa  Sdera, Ahmed A. Edeep and Abdelhamed Ebzabez.

      Der Pharma Chemica, 2014, 6(2):234-238.

14.   Synthesis, characterization and analgesic activity of several new n-substituted phthalimide analogues

      Author(s)  Omran Fhid, Shaban E.A. Saad , Talal H. Zeglam, Asma Eswayah , Jamal Baki , Esra

      Alnnas ,   Yousra Haroon , Majda Zitouni  and Wafa Sdera.

      IJPSR, 2014; Vol. 5(8): 3199-3203  

15.    Synthesis, characterization and anti-microbial activity of some novel ester-ether phenol derivatives.

      Author(s) Talal H. Zeglam, Omran N. R. Fhid*, Asma.Gebril, Massud A.S.Anwair, Reham

      M.Mufti and Zakia A.Ghanfoud

      European journal of biomedical  and  Pharmaceutical sciences , 2015, 2 (3): 91-96

16.   Synthesis, analgesic and antieplieptic properties of some novel n-substituted succinimide

      Author(s) Omran N. R. Fhid., Talal H. Zeglam, Shaban E. A. Saad., Mohammed. Sh. Shlaka.,

      Mohammed.A. Dao

      World journal of pharmacy and pharmaceutical sciences, 2015, 4( 06): 24-34..

17.   Synthesis and Pharmacological activity of N-substituted Succinimide analogs

     Author(s) Omran N. R. Fhid., Talal H. Zeglam., Shaban E. A. Saad .,Suaad M. Abuskhuna.,  

     Rowida .M. Alglad., Hana. M.Gamberlou., Nabila. B.Masoud

International Journal of PharmTech Research, 2015, Vol.8, No.3, pp 434-439.

18.   Synthesis and antimicrobial activity of some new phthalimide derivatives

Author(s) Talal H. Zeglam , Omran N. R. Fhid , Suaad M. Abuskhuna , Asma.Gebril1, Mohamed .A.Edweshia ,  Fouad.A.Abonaja , Ramy.Y.Krsift , Moad. M. Dardor

      Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry, 2015m 3(3),154-161.

19.    synthesis, characterization and antimicrobial activity of some new phthalimide derivatives.

     Author(s) Omran Fhid, A.m.doma , Talal H. Zegla,  Jamal Baki ,  Majda Zitouni  and Wafa Sdera,

      Der Pharma Chemica, 2015,  7 (11), 240-242.

20.    Synthesis and Pharmacological Evaluation of Some New Schiff Bases of Succinimide

Omran Fhid , Massud A. S. Anwair, Talal H. Zeglam, Shaban E.A.Saad, Areej.J.AL Aswed, Zahra .M.AL Aswed.   Journal of Chemical, Biological and Physical Sciences,  2017, Vol. 7, No. 3; 605-613  

21.   Synthesis and analgesic activity evaluation of some new benzimidazole derivatives

Asma Eswayah, *, Souad Khaliel, Shaban Saad3, Naima Shebani,Omran Fhid, Amal Belaid, Tawssul Alsharif, Haneen Elforjane,Yousra Saadalla, Ennam Baga.

American  Journal of Chemistry and Application, 2017; 4(5): 30-35

22.   Synthesis and biological evaluation of some novel schiff bases of benzimidazole derivatives

  Author(s)  Asma Eswayah1, Rima Hermas, Souad Khaliel, Rehab R. Walli, Amal Belaid1, Omran  Fhid1, Marwa Elmelady ,  Esraa Elhaddad1, Fadilah Aleanizy4 and Fulwah Alqahtani

  European journal of biomedical and pharmaceutical sciences, 2018,  Volume: 5 ,Issue: 3, 11-16.

23.  Virtual Screening Of N’-Methylene-1H-Indole2-Carbohydrazide Schiff ‘s Base Derivatives as

       Cyclooxygenase Inhibitors.

        Amira A Sadawe , Omran Fhid, Inass A Sadawe , Nisreen H Meiqal, Abdulathim A A  Alshoushan, Salah

       M Bensaber  Anton Hermann  and Abdul M Gbaj,. lLupine Online Journal of Medical Sciences., volium 4,

       issue 2,   376-379, 2019

24.    Virtual Screening of Phenylenediamine Schiff`s Base Derivatives as Possible DNA Intercalating Agents.

 Nisreen H Meiqal1, Bushra E Ammar1, Inass A Sadawe1, Abdulathim A A Alshoushan2, Salah M Bensaber1, Omran Fhid1, Anton Hermann3 and Abdul M Gbaj., Biomed J Sci & Tech Res., Volume 24- Issue 3., 18381-18332.,    10.1.2020

25.    In silico studies of 2-(4-(aminomethyl)phenyl)isoindoline-1,3- dione Schiff base derivatives as potential inhibitors against main protease COVID-19 enzyme

Areej A. Al amara1 , Omran N. Fhid1 , Inass A. Sadawe1 , Nisreen H. Meiqal1 , Salah M. Bensaber1 , Massaud S. Maamar2 , Anton Hermann3 and Abdul M. Gbaj1. Mediterr J Pharm Pharm Sci 1(1): 12-17, 2021