Abstract
Frontal fibrosing alopecia (FFA) a variant of lichen planopilaris (LPP) described a gradual recession affecting the frontoparietal region in postmenopausal women, with the stark difference between the pale, smooth skin and the sun-damaged skin on the forehead, By trichoscopy, there’s a lack of hair follicle openings and the presence of perifollicular erythema at the hairline. With histopathological features include lymphocytic infiltration and fibrosing of the root sheet of hair follicle. We aimed to determine the relation between the duration of the disease and response to early initiation of different treatments. We conducted a retrospective study, including 16 cases of FFA from Tripoli Central Hospital, spanning from November 2019 to November 2023. In this study, we used data extracted from patients' follow-up records, which included information on demographics, disease history, examination results, trichoscopy findings, and administered treatments. The process of data entry and analysis was conducted using SPSS 26. We found out of 16 participants which were all females, mean age of 53.50 (±4.94), history of duration in months was 54 (42-62). There was a statistically significant negative strong association between the response to the treatment and the duration of the disease, τb = -0.574, p-value = 0.011.