Abstract
This clinical investigation aimed to identify factors leading to fixed partial denture failures and their implications, crucial for enhancing clinical outcomes. Conducted in Tripoli, Libya, with 75 patients contributing 235 units, the study utilized John F. Johnston's and John J. Manappallil’s classifications to categorize failure causes. Mechanical issues, predominantly in female patients, were identified as the primary cause of dental bridge failure, particularly in porcelain fused to metal (PFM) bridges with a "Fixed-Fixed" design, mostly in the upper jaw. The study underscores the importance of a multifactorial approach in preventing and managing fixed partial denture failures, emphasizing meticulous prosthesis design, manufacturing, and placement, alongside patient selection, diagnosis, treatment planning, and oral hygiene education.