Abstract
Background: Childhood epilepsy is a common cause of neurological morbidity (incidence 4- 7.8/10,000); early recognition and treatment are keys to the best possible outcome. Social impact in childhood is often severe, producing isolation and loss of self esteem. Objective: To determine the Efficacy of Na valporate as monotherapy in different types of epilepsy & in different pediatric age groups and to define side effects of Na valporate. Methodology: cases series from 150 cases were randomly selected from files of patient whose in regular follow up in neurology clinic at Tripoli Pediatric Hospital, in period from January 2006 to December 2009; data collected by using a preformed case sheet which contain following items Sex, Age including current age, age of onset of seizure, time of valporate introduction, period of regular valporate intake, Type of seizure, Duration of seizure, Frequency of seizure, Neonatal history, Developmental history, Neurological examination, Family history, EEG& MRI finding, History of previous antiepileptic medication, Seizure control, Adverse effects of valporate.