Abstract
Human beings are exposed to agrochemicals either directly during application or indirectly through the consumption of pesticide-treated agricultural crops. The purpose of this study was to investigate the side effects of an insecticide commonly used in the agricultural field THM by studying its toxicity on animals and the anti- toxic effects of ascorbic acid. The results showed the great role of vitamin C in decreasing oxidative changes from exposure to THM. Therefore, vitamin C intake is important to reduce the negative effects of THM. In addition, vitamin C can be useful in reducing the toxic effects on various organs in individuals who deal with pesticides on a regular basis through field application. For occupational pesticide exposure, prophylactic vit C (≥500 mg/day) may mitigate oxidative damage, though human trials are needed.