Abstract
Direct comparative data on periodontal regeneration (PR) versus extraction and implant placement remain limited. Tooth‐specific periodontal conditions such as furcation involvement and overall tooth prognosis may dictate success or failure of such treatment. Methods A retrospective analysis was conducted on patients undergoing periodontal regenerative procedures or dental implants at the University of Michigan periodontics clinics. Clinical outcomes were assessed, including tooth and implant survival, success rates, and complications. Cost‐effectiveness was evaluated using the incremental cost‐effectiveness ratio (ICER). Results In a cohort of 130 subjects (176 sites; 88 PR‐treated teeth and 88 implants; mean age 63.7 ± 12.7 years) followed for 6.4 years on average, no differences in survival or success rates were found (odds ratio [OR] = 0.36, p = 0.2, and OR = 0.77, p = 0.56,