Abstract
fine needle aspiration cytology FNAC is a rapid minimally invasive and cost effective method for evaluating thyroid lesion , however, its diagnostic performance varies depending on sampling technique, adequacy and cytological interpretation, AIM : this study aimed to asses the diagnostic accuracy of FNAC compèred with Histopathological examination.MATERIAL AND methods: A retrospective cross - sectional study was concluded on patients who underwent Thyrodectomy at department of surgery , HEAD and neck Surgery , between June 2023 and October 2024 , FNAC results was classified using the BETHESDA system and compèred with final HPE , diagnostic indices, including sensitively , specificity, accuracy, positive predictive value PPV and negative predictive value NPV were calculated using jamovi.RESULTS : thirty five patients were included ( mean age 43.5 +-13,6 years 94 % female) FNAC showed a sensitivity 77,8% specifity of 52,9% , accuracy of 65,7 % , PPV of 63,6% and NPV of 69,2 %when compared with HPE . the majority of malignant lesion were papillary thyroid carcinoma. CONCLUSION :FNAC continues to be a valuable first line diagnostic tool for thyroid nodules , demonstrating good sensitivity but moderate specificity . HPE remains crucial for a definitive diagnosis . larger , multicenter studies are recommended to validate these findings and to enhance diagnostic reliability through better sampling and cytological expertise.