Abstract
Periodontitis is an inflammatory disease caused by Gram-negative bacteria, causing recession or pocket formation in tooth-supporting structures. As the disease progresses, pocket formation occurs due to deepening gingival sulcus. Chronic periodontitis is associated with anemia. (ACD) characterized by increased cytokine production and impaired erythroids colony formation. The objective of this study is to assess the correlations between the clinical periodontal parameters and hematological parameters in patients with chronic periodontitis (CP) and healthy periodontium subjects. To evaluate the relationship between periodontitis and anemia. The present cross-sectional study was carried out in the Clinic at Abu Salim Trauma center, Tripoli. We randomly selected 100 subjects. Male and female systemically healthy adult patients aged (20-60) years and divided into two groups: 80 samples with chronic periodontitis and 20 samples with healthy periodontum. A sample included systemically healthy adult patients showing clinical signs of periodontitis (reddening, loss of stippling, bleeding on probing). Blood samples will be obtained for both groups during the examination visit to investigate hematological parameters (CBC). Further, the values were gathered and subjected to statistical analysis T-test was performed to assess the statistical significance between the groups. A standardized questionnaire was used to obtain data. The current study revealed lower values of RBC, Hb%, HCT, MCV, MCH, and MCHC, and found that patients with periodontitis had lower hematological parameters. Our findings showed lymphocyte and neutrophil count is higher in the group with periodontitis than in the healthy group. The results showed a statistically significant difference in (MCH), which was lower in patients with periodontitis, while it is generally understood that decreased MCH values were indicative of microcytic anemia. This study showed decreased hematological parameters RBC.