Abstract
Background: Postpartum ovarian dysfunction [ovarian cyst (OC) and persistent follicle (PF)] has been an importantissue. Finding effective hormonal treatments to improve reproductive performance in dairy cows has become anecessity.Aim: Improve reproductive performance and ovarian activity in postpartum cows with specific customized treatmentfor OC and PFsMethods: The study included 48 cows at 14 days P.P, which received two dosages of 500 μg IM cloprostenol, 14 daysapart as presynchronization protocol. Ultrasound ovarian scans 14 days after the last injection for 4 weeks. The cowswere divided into three groups according to ovarian status: OC (n = 14), PF (n = 12), and NE (n = 22). In the OCgroup, received 500 μg IM cloprostenol and 100 μg IM cystoriline, a second dose of cloprostenol 14 days later and asecond dose of cystoriline 36 hours later, and AI after 24 hours (GnRH+ PG/PG/GnRH). In the PF group, was fittedwith progesterone-releasing intravaginal device (PRID) for 9 days; the same day, they received 100 μg cystoreline then500 μg cloprostenol 7 days later, after PRID removal AI 56 hours later (PRID + GnRH/PG). In the NE group, artificialinsemination was implemented until 28 days depending on estrus detection.Results: The ovarian activity was greatly affected by the customized treatments, leading to enhanced follicular andluteal activity, particularly after the PGF2α injection. The OC and PF groups showed substantial estrus responses of71.43% and 75.02%, respectively, during AI time. While the NE group had an ovulation rate of 54.5% and a pregnancyrate of 31.8%, the treatment groups showed marked improvements in reproductive performance. The ovulation ratesin the OC and PF groups were 71.43% and 75% and the pregnancy rates at the 1st artificial insemination were 64.28%and 66.7%.Conclusion: Improving reproductive performance and minimizing the time to first service are possible advantages ofearly case-specific treatment for postpartum cows with OC and PFs. (PDF) Customized modified therapies for ovarian cyst and persistent follicle followed with TAI in early postpartum dairy cows. Available from: https://www.researchgate.net/publication/380309503_Customized_modified_therapies_for_ovarian_cyst_and_persistent_follicle_followed_with_TAI_in_early_postpartum_dairy_cows [accessed Oct 06 2026].