Abstract
Background: Pseudomonas aeruginosa is one of the most invasive organism that causes severe tissue damage in diabetic foot ulcers. A major problem in P. aeruginosa infection because of that it is commonly exhibits a high degree of resistance to antimicrobial agents .To improve appropriate antimicrobial therapy and reduce the incidence of antibiotics resistant bacteria, information on the antibiotic susceptibility to this bacterium is urgently needed. Therefore, the aim of this study was to isolate and determinate the antimicrobial susceptibility of the P. aeruginosa in diabetic foot ulcers patients. Methods: This study was carried out over the period between June 2014 to April 2015 at Tripoli Medical Center. A total of 120 bacterial isolates were cultured onto bacteriological media such as nutrient agar, MacConkey agar and blood agar. Identification of retrieved bacterial isolates was done using standard diagnostic microbiological laboratory methods and antibiogram was determined by VITEK ® 2 compact automated system. Results: Twenty one strains of P. aeruginosa from 120 diabetic foot ulcers were detected. P. aeruginosa isolates exhibited multidrug resistance to Ampicillin, Augmenting, Cefuroxime, Cefoxitin, Cefazolin, Ceftriaxone, Trimethoprim/sulfamethzole, Piperacillin. However, all isolates of P. aeruginosa were 100 % sensitive to Imipenem. Conclusion: P. aeruginosa infections of diabetic foot ulcers patients have multi-drug resistant. Imipenem is the empirical antibiotic of the choice. Key words: Pseudomonas aeruginosa, diabetic foot ulcer, antibiotics resistance arabic 17 English 114