Abstract
The effects of X-irradiation on electrical properties of rat liver, kidney and muscle tissues are studied. Multiple frequency bioelectrical impedance analysis (MFBIA) method is used to describe change in electrical properties of the irradiated tissues as a function of frequency and time, frequency dependence of conductivity and relative permittivity are measured. The rats were, whole body, exposed to (400 rads) X-rays from a clinical therapeutic 6 MV linear accelerator. At time intervals, the excised samples were obtained by sacrificing rats according to experimental (1, 2, 4, 9, 16, 23, 30 day post-irradiated). Electrical impedance of each excised sample is measured between 100 Hz to 5 MHz for (93) frequency points. Changes in electrical properties and readings at low, intermediate and high frequency as function of time for all samples reveal that there exist significant differences between both conductivity and permittivity of non-irradiated and irradiated muscle tissues (p < 0.05). At high frequency (1 MHz), the conductivity values (0.67 4 to 0.767 S/m) of longitudinal muscle and (0.582 to 0.731 S/m) of transverse muscle of irradiated tissues for all times, are higher than non-irradiated values (0.573 and 0.546 S/m) respectively. The differences in conductivity values between non-irradiated and 30 days post-irradiated, for longitudinal and transverse muscles are (34.103% and 33.922 %) respectively. The normalized values of relative permittivity at both low (5KHz) and high (1 MHz) frequencies are (26.38% and 36.641%) and (44.901% and 18.202%) for longitudinal and transverse muscles respectively. No significant differences in the conductivity and permittivity for liver and kidney were observed. Statistically significant differences observed only in muscle tissues therefore the effect due to whole body exposure are appeared more rapidly at 30 days in the muscle tissue than other organs (liver and kidney).