Detection of HER-2 receptor over expression in Breast Cancer by using of Immunohistochemistry procedure

Date

2019-3

Type

Conference paper

Conference title

International Conference on Technical Sciences (ICST2019)

Author(s)

Mohamed Abuagela
Abulgasem Dakhil

Abstract

Abstract Immunohistochemistry (IHC) is a technique used to quantify the expression of biomarkers in antigens and tissues by making them visible. The IHC technique is based on a binding reaction. Human epidermal growth factor receptor 2 (HER2) is a receptor protein present on the surface of cancer cells and used as an indicator for breast cancer Four paraffin-embedded breast sections were shown positive HER-2 expressed cells. The percentage of positive cells of carcinoma breast tissue was 6% whereas the percentage of normal tissue was less than 1%.

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