Abstract
Aim of this work is to verify the role played in chromatographic technique by innovative MONOLITHS In m RNA VACCINE production: material used, technology and products for large scale production. The fact that a great producer use carbon composite in monoliths is of great interest: carbon fibre reinforcement embedded into epoxy thermoset resin. It is also verified the role played by silica products for chromatographic use and its origin (synthetic or from natural product like Rice). Related the product form Rice it is used as pharmaceutical excipient. Also in this cases other great chemicals producer in its website for SILICA GEL for chromatography report a reference related the production of silica form Rice. (Not only systetic so) Of interest the profile of impurity of this product if used in resin column for purification biopharmaceutical and in particular the carbon content.