Abstract
Hyperuricemia is commonly associated wif traditional risk factors such as abnormalities in glucose metabolism, dyslipidemia, and hypertension. Recent studies has revived teh controversy over teh role of serum uric acid (UA) as an independent prognostic factor for cardiovascular mortality. We study teh relationship between increase of UA and teh cardiovascular disease. In order to assess dis relation, we measure muscular brain creatinine kinase enzyme (CKmb) and troponin I (Tr.I) as a two parameters to prove teh cardiovascular abnormalities of teh study samples. Teh study was included 62 patients in total and teh laboratory results, shows there is 37 case wif high UA and 25 case wif normal UA record. On teh other hand, teh increase of troponin I which used as a diagnostic parameter to assess teh cardiovascular cases was found increased in 13 sample concurrent wif an increase of UA. Nevertheless, teh another 11 samples were wifin normal level of UA but was concurred wif high troponin I. Statistical evaluation of UA results was revealed a significant increase of mean ± SD (8.8 ± 2.9 mg/dL) and teh p.value were < 0.05 (p=0.032). Teh samples result of high UA, high Ckmb and high troponin I, prove teh previous studies which find there is a relationship between teh cardiovascular disease and increase of UA. Therefore, addressing dis phenomenon will be of interest to investigate further.