Abstract
ackground and aims. Patients with type 2 diabetes exhibitsubclinical inflammation and nearly all signs of systemicinflammation, which characterized by high circulating levels ofinflammatory parameters. The current study aimed to assess thelevels of the inflammatory markers such as, C-reactive protein(CRP), Erythrocyte sedimentation rate (ESR) and leukocyte counts(WBC) count in patients with T2DM and to correlate their valueswith the HbA1c levels. Methods. This cross-sectional study wasconducted on 41 consecutive patients with type 2 diabetes attendingthe outpatient department of Tajoura-Heart Hospital. All patientswere had laboratory investigations including; Hemoglobin A1c(HbA1C), C-reactive protein(CRP), Complete blood count(CBC) andErythrocyte sedimentation rate (ESR). Patients were assessedaccording to glycemic status, patients with under control of diabetics(HbA1C level was equal to or less than 7.5%), and patients withpoorly controlled diabetics (HbA1c level was greater than 7.5%).Results. Statistically significant association was observed betweenESR, CRP levels and level of HbA1c. The ESR and CRP level weresignificantly higher in poorly-controlled diabetic patient than whowith well controlled diabetics (p value= 0.037 and 0.017respectively). WBC levels were higher in patients with poorlycontrolled than well controlled patients but the difference was notstatistically significant (p value= 0.771). Conclusion. Inflammationand glycemic control have a strong association in patients with type2 diabetes, suggesting that inflammation plays a role in diabetespathogenesis. (PDF) Association Between Some Inflammatory Markers and HbA1c in Patients with Type 2 Diabetes Mellitus. Available from: https://www.researchgate.net/publication/369686801_Association_Between_Some_Inflammatory_Markers_and_HbA1c_in_Patients_with_Type_2_Diabetes_Mellitus [accessed Nov 01 2023].