Abstract
ABSTRACT Background and aims: Chronic kidney failure is one of the leading causes of death among Libyans in the city of Tripoli. About one billion people in the world suffer from vitamin D deficiency or insufficiency. Moreover, many data points indicate that vitamin D insufficiency and deficiency are highly prevalent among patients with chronic kidney disease (CKD) or undergoing dialysis. This study aimed to evaluate the level of vitamin D for dialysis patients at Tripoli dialysis and treatment center. Methods: Samples from 140 (patients and control groups) represented by 53 males (37.9%) and 87 females (62.1%) were included in the study. Samples from 104 dialysis patients and 36 healthy (control) group were included in this study. Data was collected during two months from the beginning of June 2023 to the end of July 2023 with the aid of a structured questionnaire (data collection form). One hundred and forty patients visiting Tripoli dialysis and treatment center were interviewed. Blood samples were collected from candidates; Clinical investigations data collected included vitamin D, urea, creatinine and PTH hormone levels measurement. The collected data was entered in Microsoft Excel and was analyzed in the Statistical Package for the Social Sciences (SPSS) version 27. Results: The current results of this study showed that the dialysis participants with insufficient level was (37%), followed by deficient level with (30%) while those with adequate and severe deficiency level were (28%) and (5%) respectively. The result of independent Sample (T) test that was performed to compare vitamin D level between dialysis patients and control group expressed as (M=25.03, SD= 11.10) and (M=21.06, SD=14.94) respectively; which revealed that there were no significant differences between them with P value =0.094. Furthermore, there was a weak negative correlation between serum vitamin D and creatinine (r = -0.364-, p= 0.255), between vitamin D and PTH (r= -0.378-, p=0.226), and between vitamin D and urea (r = -0.347-, p=0.269). Conclusion: Obviously, although vitamin D deficiency is strongly linked to kidney failure, the tests that work of this disease are limited, so introducing a vitamin D for dialysis patients with CKD helps in understanding the patient's condition and helps in disease management. Keywords: Vitamin D vitamin D deficiency vitamin D insufficiency chronic kidney disease.