PH536 : Toxicology & Drugs

Department

Department of Public Health

Academic Program

Bachelor in public health

Type

Compulsory

Credits

03

Prerequisite

Overview

1

Course code and title

PH536 - Toxicology and Drugs

2

Course coordinator

Dr. Ahmed M.Mesawi

3

Course type

Specialized course

4

Prerequisites code

5

Department /Division offering the course

Public Health

6

Departments teaching the course

Public Health

7

Total credit hours

3 credit- 3hrs /week

8

Language of instruction

English

9

Level of course (Year/Semester)

3rd Year/ Fifth semester

10

Date of specification approval by Council

2004-2005

Intended learning outcomes

1. Understand the fundamentals of toxicology and ecotoxicology.

2. Apply toxicology principles to the fate of toxicants and contaminants in the environment.

3. Characterize the biological impacts of toxins and contaminants on “organic life”.

4. Critically evaluate environmental toxicology topics in the media and the science behind these studies.

5. Be able to critically evaluate, discuss, explain, and present current topics in environmental

6. Describe molecular, cellular and pathophysiological responses resulting from exposure to chemical agents relevant to human health.

7. Identify underlying susceptibility factors which contribute to the ability of chemicals to elicit bio effects which contribute to human disease

A. Knowledge and Understanding

A.1

Understanding critical mechanisms of toxicity in humans.

A.2

Understand the relation between toxicant and human been (toxic kinetic, toxic dynamic).

A.3

Describe toxicity rating, potency and LD50.

A.4

Explain toxicokinetic, toxicodynamic.

B. Intellectual Skills

B.1

Distinguish between different types of elimination by using of antidote.

B.2

Uses of poly antivenom.

B.3

Explain the basic principles of toxicology, including dose-response, and the physiological processes that determine the fate of toxin in the body.

B.4

Evaluate the risk that exposure to chemicals in the environment will cause toxicity and disease in humans.

C. Professional and Practical Skills

C.1

Compare between various type of Alkaloid (Plant poisoning)

C.2

Detection and identification of suspected specimen.

C.3

Retrieve toxicology information from public health effects databases, interpret the information, and use scientific evidence to explain the roles of environmental toxicants in human disease.

C.4

Recognize and classify prescription / non-prescription drugs and their clinical indications as commonly seen in clinical practice.

D. General/Transferable Skills

D.1

Understand and be able to explain and differentiate between deferent drugs and drug substances.

D.2

Distinguish between addicting and habituating agents (drug abuse).

D.3

Describe the divisions, sources and classification of poisons.

D.4

Describe the prevention , diagnosis , and treatment of poisoning.

Teaching and learning methods

1. Lectures.

2. Assignment

3. Presentation

Methods of assessments

Assessment Method

Due (week)

Weight (%)

Notes

1

Midterm exam

Week fifth and tenth

20%

Written

2

Oral exam

3

Practical exam

4

Assignments/HWs

Week seventeen and eighteen

70%

Written

5

Final exam

Week four and week twelve

10%

Quizzes

Total (%)

100%

Course References

Type

Title

Publisher

Edition

Author

Availability

Lecture notes

Textbook

Essential toxicology

Casaret Doultis

2003

Klassen

Library of faculty

Reference books

General toxicology

Library of faculty

Modern med toxicology

Tay pee

2005

W.pilly

Library of faculty

Clinical Toxicology

3ed

Sawsan shalaby

Library of faculty

Periodicals

Journal of Toxicology

_______

______

_______

open access journal

Websites

http://ocw.jhsph.edu/index.cfm/go/viewCourse/course/publichealthtoxicology/coursePage/lectureNotes/

Other