Abstract
background: Apoptosis plays an important role in both human embryonic development and adult tissue homeostasis. The most common mechanism by which the body eliminates damaged or unneeded cells without local inflammation from leakage of cell contents. Survivin is an inhibitory of apoptosis protein that can block an apoptotic pathway. Overexpression of survivin has been detected in many human cancers and found to be associated with disease progression, recurrence, low survival and increased resistance to anti-cancer therapies