Abstract
Nanocapsules are colloidal particles with dimensions measured in nanometers and generally obtained in the range of 100 to 500 nm through nanoencapsulation technologies. Nanoencapsulation encapsulates nano-sized particles in liquid or solid form to create nanocapsules or nanoparticles. Generally, six classical methods are involved in nanocapsule formation: nanoprecipitation, emulsification-diffusion, double emulsification, emulsification-coacervation, polymer coating, and layer-by-layer. Nanocapsules are prepared from different monomers and cross-linked polymers, contributing to their stability during and after encapsulation. They are segregated into ionic and non-ionic by the surface formal charges, which then influence the type of applications. The applications of nanocapsules usually range from developing targeted drug delivery systems, self-healing materials, and the encapsulation of nutritive additive compounds in nutraceutical products. Nowadays, people turn their attention to natural resources. Therefore, the polymer matrix and the active substances in nanocapsules have been adopted with various natural polymers such as protein, lipids, polysaccharides, plant metabolites, plant exudates, or plant extracts. Since nanotechnology products are predicted to be broadly utilized in the future, major key players must work collectively to handle the issue of safety regulation and user acceptance as well as optimum scale production of nanocapsules in industries.