PS142 : Physiology II

Department

faculty of Medicine

Academic Program

Bachelor in Medicine and general surgery

Type

Compulsory

Credits

04

Prerequisite

PS141

Overview

This course:

  • Discuss the different parts, physiological functions and common pathophysiological changes of the renal system.
  • Discuss the different parts, physiological functions and common pathophysiological changes of the heart.
  • Discuss the different types of specific circulation, and the important of cardiovascular response to exercise, as well as the physiology of shock.
  • Discuss the components of an ECG tracing.

Intended learning outcomes

  • By the end of the course, the student will be able to:
  • Understand the different parts, physiological functions and common pathophysiology of the renal system.
  • Understand the different parts , physiological functions and common pathophysiology of the heart.
  • Understand the different types of specific circulation, the important of cardiovascular response to exercise, and the physiology of shock.
  • Understand the Electrocardiogram (ECG), and its importance as investigation tool in medicine.

Teaching and learning methods

  • Lecture
  • Practical
  • Discussion

Methods of assessments

Med Term Exam --------------------- 20%

Lab -------------------------------- 15%

Final Exam ------------------------ 65%

weeksSubjectHours
1-Functional anatomy of the kidney. 1. -Major functions of the kidney. -Factors affecting GFR4
2-Tubular functions 2. -Glucose reabsorption -Renal conservation -Factors affecting Na+ excretion4
3-Tubular secretion (active secretion of H 3. + and passive secretion of K+ ions; secretion of NH3 )4
4Kidney function tests, Renal diseases 4. -Micturation4
5-Cardiac cycle-Heart sounds 5. -Cardiac output and venous return- Definitions of stroke volume, EDV, ESV ,and cardiac index – Factors affecting cardiac output - Preload and afterload6
6Regulation of cardiac function Hemodynamics: 6. Pressure, flow , resistance, and their inter-relationship (Poiseuille's law) – Hematocrit and resistance – Vascular compliance - Flow, velocity versus cross sectional area and their inter-relationship – Reynold's number - Turbulent flow and murmurs 6

7--Systemic circulation: 7. -Control of the circulation6
8-Sympathetic tone - Sympathetic vasodilator system- 8. Factors determine the VR -Blood pressure and its regulation: 5
9- Measurement of arterial blood pressure – 9. Regulation of blood pressure – Neural regulatory mechanisms - Chemoreceptors and Baroreceptors – Baroreflex – CNS ischemic reflex – Humoral regulatory mechanism – Renin-angiotensin system 6
10-microcirculation, lymphatic system, edema 6
11Specific circulation: Cutaneous circulation-pulmonary circulation-cerebral circulation-coronary circulation6
12- Circulatory shock-cardiovascular response to . exercise-Heart failure6
13, 14

-Electrocardiogram (ECG) 13. -Arrhythmias-rapid arrhythmias

-Heart block-Hypertrophy -Ischemia and infarction

12