PS243 : Physiology III

Department

faculty of Medicine

Academic Program

Bachelor in Medicine and general surgery

Type

Compulsory

Credits

04

Prerequisite

PS141PS142

Overview

  • This course:
  • Discuss the general principles of nervous system and sensory physiology.
  • Discuss the motor function of nervous system and integrative neurophysiology, and the abnormalities associated with their functions.
  • Discuss the special sense of the nervous system and the abnormalities associated with their functions. ب.iscuss the morphological, physiological function of various endocrine glands, and the abnormalities associated with بtheir function
  • Discuss the physiological functional of male and female reproductive system , and physiological changes during pregnancy and the process of fertilization and implantation, and the mechanism of labor.

Intended learning outcomes

By the end of the course, the student will learn:

  • Describe the mechanism of function of the central nervous system, sensory, motor function, and special senses system and recognize any abnormalities associated with their function.
  • Understand the morphological and physiological function of various endocrine glands, also abnormalities associated with their function

Teaching and learning methods

  • Lecture
  • Practical
  • Discussion

Methods of assessments

Med Term Exam ----------- 20%

Lab ---------------- 15%

Final Exam ----------------------- 65%

WeeksSubjectsHours
1Introduction – Review of gross anatomy and functions of CNS 1. – Formation and composition of CSF -Sensory function of CNS – Modalities of sensation – Receptors, receptor potential, adaptation, stimulus strength response – Physiology of spinal cord . 4
2Ascending tracts, dorsal column, tracts, ventrolateral system, 2. thalamus, connections and functions – Cutaneous, deep and visceral pain (referred pain) – Touch and temperature – Proprioceptor sensation – Hyperalgesia Reflexes – The reflex arc – General properties of reflexes – Synaptic and junctional transmission – Structure and function of synapse – Facilitation and inhibition – Synaptic electrical events –6
3Motor functions of CNS – Motor cortex and control of 3. voluntary movement – The pyramidal and extra-pyramidal systems – The internal capsule, basal ganglia, functions and disorders (Parkinsonism) – Upper motor neurons and lower motor neuron lesion – Cerebellum, Connections and functions – Cerebellum lesion – Equilibrium, vestibular apparatus, function of semicircular canals – muscle tone, decelerate rigidity and supra-spinal regulation.6
4The hypothalamus – Connections and functions – 4. Neuroendocrine integration – Control of autonomic functions – Limbic system and emotion hunger and thirst Electroencephalogram (EEG) – Memory, learning, speech and judgment of behaviors. - –6
5Higher functions of the CNS – The reticular activating system 5. – The electrical activity of the brain – Consciousness – Sleep – transaction of spinal cord (paraplegia) – Hemi section of spinal cord (Brown-squard syndrome6
6Hemiplegia – Parkinsonism – Tabesdorsalis – Dorsal root and 6. posterior column lesion – Syringomyelia Cranial nerve -Blood-brain barrier4
7Some common neurological disorders and abnormalities 7. Vision: Introduction – Physiological anatomy of eye6
8- Pupillary reflexes Photochemistry of vision 8. Neurophysiology of vision Color vision: 66
9The cochlea General auditory -The sense of hearing 9. mechanism Abnormalities of hearing The olfactory membranesense of taste . and smell4

10Introduction – Definition – Types of hormone – Chemistry – 10. Mechanism of action of hormones – Hypothalamic hormones and their control of pituitary hormones – Hypothalamohypophyseal portal vessels – Releasing factors and inhibitory hormone – Regulation of hormone secretion. The anterior pituitary gland (adenohypophysis) – Morphology and histology – Hormones of the anterior pituitary and their sources – Chemistry and action of growth hormone and prolactin – Control of growth hormone secretion – Chemistry and control of four trophic hormones – Disorders of growth hormone secretion – Gigantism – Acromegaly – Dwarfism – Panhypopituitarism4
11The posterior pituitary gland (neurohypophysis) – 11. Morphology and histology – Hormones secreted – Chemistry and mechanism of Action – Control of secretion. The thyroid gland – Morphology and histology – Hormones, synthesis, transport and metabolism of the hormones – Function Abnormalities of thyroid function – Anti- thyroid drugs – Thyroid function tests. 4
12Parathyroid gland – Hormonal control of calcium (Ca++) and 12. phosphorus metabolism – Distribution of Ca++ in ECF – Ca++ homeostasis – Functions of ionized Ca++ – Hormones of parathyroid gland – Chemistry, source, action and control of parathyroid hormone secretion – Role of other hormones on calcium metabolism – Abnormalities of parathyroid function. The adrenal gland – Morphology and histology – Chemistry, biosynthesis and action of hormones secreted by adrenal 4
13- The endocrine pancreas – Structure and function of islets of 13. langerhans –Pancreatic hormones – chemistry, sources, action and control of hormones – Abnormalities of their function Reproductive physiology in male – Morphology and histology of tests – Spermatogenesis – Biosynthesis, chemistry and action of testosterone – Puberty – Infertility4
14Reproductive physiology in female – Ovaries and their 14. changes from birth to puberty – Menstrual cycle and its hormonal regulation – Chemistry, biosynthesis and action of ovarian hormones Pregnancy – Fertilization and implantation – Endocrine and physiological changes – Pregnancy tests – Placental hormones – Parturition – Lactation – Development of mammary glands – Hormonal action and control – Secretion and ejection of milk – Prevention of pregnancy – Contraceptive methods4