BC 211 :

Department

Academic Program

Type

Compulsory

Credits

Prerequisite

Overview

This course deals with the study of the structure, function and properties of the biological macromolecules. Among these bio molecules are: carbohydrates, proteins, lipids, and nucleic acids .

It emphasizes on discussions of the major metabolic pathways as well as its clinical significance that results from a disruption in the normal flow of the chemical activities of such biomolecules in the human body.

Intended learning outcomes

Knowledge and understanding:

1- Demonstrate understanding of fundamental biochemistry principles

2- Learn and integrate foundational material in biochemistry to nursing career

3- Develop scientific competence in methods of inquiry and problem solving.

4- Introduce students to the cross disciplinary nature of biochemistry and its application to nursing

Mental skills:

1- Gain familiarity with the different terms and principles in biochemistry.

2- Explain and describe the synthesis of proteins, lipids, nucleic acids, and carbohydrates and their role in metabolic pathways

3- Relate the properties of the biomolecule to the pathogenesis of a metabolic abnormality.

4- Analyze structural-functional relationship of genes and proteins from bacteria.

5- Compare the different biomolecules with regard to structure and properties

Scientific and professional skills:

1- Teach the importance of the biomolecules and cite food resources.

2- Apply practical skills to study of biochemistry and related sciences

3- Recognize and respond to ethical and safety issues

4- Follow general laboratory precautions to avoid any accident and exposure to chemicals

General skills

1- Draw the chemical structure of the most commonly medically encountered biomolecule

2- Follow the procedures properly as stated in the laboratory manual.

3- Analyze data and carry out appropriate procedures and computations

4- Effectively communicate through a range of different methods

Research on updates of biochemistry and discuss.

Teaching and learning methods

• Lecture-discussion

• Group Dynamics

Laboratory Experiment.

Methods of assessments

• Midterm exam 30%.

• Practical Exam 12%

• Final exam 50%.

• Assignments/HWs/Quizzes 8%.

Course Outline

Overview of chemistry

· What is an Atom?

· Structure Of Atom.

· Atomic Number Z

· Atomic Mass Number

· Periodic Table

· The cell: Structural and functional unit of all living organisms

· Cell Theory

· Dalton Atomic Theory

· Bohr’s Model of Atom

· Isotopes

· Compounds, Mixtures and Solutions

· Cell Structure and Function

· Basic Cell Substances

· Cell Types

Overview of Biochemistry

History of Biochemistry

Overview of the Biomolecules

Overview of Cellular Process

Carbohydrates Types

· Monosaccharide's

· Stereoisomer's and Stereochemistry

· Biologically Important Monosaccharide's

· Biologically Important Disaccharides Polysaccharides

Carbohydrate Metabolism

· Overview of Catalytic

· Processes Glycolysis

· Fermentations

· The Pentose Phosphate Pathway Gluconeogenesis:

· The Synthesis of Glucose

· Glycogen Synthesis and Degradation

· Chemistry of lipids

· Definition

· Chemical Structure of lipids

· Biological importance of lipids

· Classification of lipids

· Simple lipids

· Fatty Acids

· Classification of Fatty Acids

· Saturated Fatty Acids

· Structure of Saturated Fatty Acids

· Mono Saturated Fatty Acids

· Poly Un Saturated Fatty Acids

· Essential Fatty Acids

· Functions of Essential Fatty Acids

· Cis and Trans Fatty Acids

· General properties of fatty acids

· Glycerol

· Importance of glycerol

· Triglycerides

· Types of triglycerides

· General properties Triglycerides

· Complex Lipids

· Derived Lipids

· Functions of lipids

Fatty Acid Metabolism

· Lipid classification

· Fatty Acid Degradation

· Fatty Acid Synthesis

Protein Structure and Function

· Cellular Functions of Proteins

· The Alpha-Amino acids

· The Peptide Bond

· The Primary Structure of Proteins

· The Secondary Structure of Proteins

· The Tertiary Structure of Proteins

· The Quaternary Structure of Proteins

· Amino acids structure and its classification

· Classification on the basis of nutrition

· Classification of amino acids on the basis of catabolism

· Biological importance of proteins

Enzymes

· Nomenclature and Classification

· Regulation and Inhibition of Enzyme Activity

· The Enzyme-Substrate Complex

Nucleic acid

· Introduction of nucleic acids

· The structure of nucleotide

· The structure of nucleoside

· The structure of DNA and RNA

· Classification of DNA and RNA

· Comparison of DNA and RNA structure

(AR 101)
(ST 101)
(NU 112)
(NU 111)
(EL 101)
(AN 111)
(EL 102)
(SO 101)
(PS 111)
(NU 113)
(AR 102)
(CS 101)
(BC 211)
(NU 201)
(NU 202)
(NU 211)
(EL 201)
(PT 211)
(MB 211)
(EL 202)
(PC 211)
(PA 211)
(NU 213)
(NU 221)
(NU321-ICU)
(NU 312)
(NU322-OT)
(NU322-MN)
(NU322-ICU)
(NU322-GN)
(NU321-OT)
(NU321-MN)
(NU321-GN)
(NU 311)
(NU 310)
(NU 320)
(NU325-MN)
(NU325-OT)
(NU 300)
(NU325-ICU)
(NU325-GN)
(NU324-MN)
(NU 313)
(NU 323)
(NU324-OT)
(NU324-ICU)
(NU324-GN)
(NU423-GN)
(NU423-ICU)
(NU423-MN)
(NU424-GN)
(NU424-ICU)
(NU424-MN)
(NU 400)
(NU 420)
(NU425-MN)
(NU 401)
(NU 410)
(NU426-OT)
(NU426-MN)
(NU426-ICU)
(NU426-GN)
(NU425-OT)
(NU425-ICU)
(NU425-GN)
(NU 421)