This course introduces
the students to the methods used in drug development, including:
The general methods used to screen a new drug and to determine its efficacy
using biological organisms.
The general methods that are used in the examination and bio-calibration of
drugs that act on different systems of the body: nervous system, cardiovascular
system, digestive system...etc
Introducing the students to the clinical stages of drug testing.
Course outlines:
introduction for bioassay and general methods for drug screening.
methods for bioassay of drugs such as drugs affecting the central and autonomic nervous system, the cardiovascular system, and the digestive system, in addition to diuretics and hormones.
Pre-clinical and clinical stages of drug screening.
Intended learning outcomes
At the end of the course,
it is expected that the student should:
Have sufficient skills and knowledge needed for the development of new drugs.
Have knowledge of the methods used for biological testing of drugs acting
on the autonomic nervous system, hormones, and the central nervous system.
Have knowledge of the methods used for biological testing of drugs acting
on the circulatory system, diuretics, and digestive system.
The student will be familiar with the pre-clinical and clinical stages of
drug testing.
Teaching and learning methods
Lectures
Laboratory
activities
Group discussion
Methods of assessments
The students' knowledge and performance about the
studied topics are assessed throughout the study period. These assessment
methods include:
quizzes and discussion sessions.
practical and oral exams.
written exams.
References
Essentials of Bioassay and Screening of Drugs. Elhwuegi AS and Ahmed SS. Dar-Alhikma. Malta
