P411T : Medicinal Chemistry 2

Department

faculty of Pharmacy

Academic Program

Bachelor in pharmaceutical sciences

Type

Compulsory

Credits

04

Prerequisite

P312T

Overview

This course is a continuation of the pharmaceutical Chemistry 1 (P312T). It aims to enable students to acquire modern knowledge of these specialized topics in the course. The topics are taught according to the vocabulary approved by the college specifically to meet the students knowledge needs. For example:

  1. . The relationship between the chemical composition of drugs, their biological effects, and their therapeutic effects.
  2. How to develop and design medicines and the extent of their therapeutic effect on some diseases.
  3. Transfer of technology design laboratories to the practical application laboratories for the synthesis and testing of these drugs.
  4. Basic and different methods of drug synthesis and pharmaceutical analysis, and understanding the results from biological experiments in practice
  5. Study of the functional groups in the compound and the relation of their biological effects on the various functions of the organs.
  6. .applying the basic concepts for the students, which were studied in the course medicinal chemistry 1, for example, the concept of latent drug- the relationship of drug efficacy and the role of the liver for it through metabolic processes-how to make the effectiveness of some drugs have a features of longer acting effect.
  7. Providing students with the basics of medicinal chemistry by knowing the chemical structure of many groups of drugs, which include: The central nervous system, the circulatory system, blood vessels, hormones such as insulin, hypoglycemic agents, antihistamines, and anticancer drugs.

Course outlines:

  1. histamine and histamine antagonists 
  2. analgesics and NSAIDs
  3. drugs affecting central nervous systems.
  4. Diuretics and drugs used for cardiovascular diseases
  5. Hormones, hypoglycemic agents, and drugs affecting the thyroid gland.

Intended learning outcomes

  1. . Learn about recent development in the field of medicinal chemistry
  2. Describe the new information in the selected topics
  3. . Integrate key information and suggastions for control and design from different sources.
  4. Applying a wide range of synthesis and measurement techniques and devevolp appropriate practical skills in the workplace
  5. application of different chemical methods and techniques of drugs synthesis
  6. Evaluation of the final results of research in the filed of medicinal chemistry
  7. Making professional decisions in the field of specialization
  8. Report writing and submission

Teaching and learning methods

A wide range of teaching and learning methods to suit the content of the course including theoretical lectures and laboratory lessons in addition to panel discussions

Methods of assessments

Evaluation methods vary widely to suit the nature of the course. They include written exams, which represent 60% of the total score for the course, in addition to short tests, research, laboratory reports, and practical or theoretical practical exams, which represent 40% of the total score.

References 

Foye's Principles of Medicinal Chemistry. Eighth edition, International Edition. byVictoria Roche PhD F. and Thomas Lemke


Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry 12e


Burger's Medicinal Chemistry, Drug Discovery and Development, Volumes 1 - 8, 8 Volume Set, 8th Edition